|
|
H+ + salicylate + ATP <=> (2-hydroxybenzoyl)adenylate + diphosphate
|
2.7.7.58
(2,3-dihydroxybenzoyl)adenylate synthase
6.2.1.61
salicylate---[aryl-carrier protein] ligase
6.2.1.65
salicylate---CoA ligase
|
–
–
–
|
| |
BRENDA:
BR53008;
BR53122
KEGG:
R12640
MetaCyc:
RXN-11113
|
|
|
|
2,5-Dihydroxybenzoate + O2 <=> maleylpyruvate + H+
|
1.13.11.4
gentisate 1,2-dioxygenase
1.13.11.86
5-aminosalicylate 1,2-dioxygenase
|
–
–
|
| |
BRENDA:
BR36757
KEGG:
R02656
MetaCyc:
GENTISATE-12-DIOXYGENASE-RXN
SABIO-RK:
2552
|
|
|
|
2,5-dihydroxybenzoyl-CoA + H2O <=> 2,5-Dihydroxybenzoate + CoA + H+
|
3.1.2.23
4-hydroxybenzoyl-CoA thioesterase
|
–
|
| |
MetaCyc:
RXN-11741
SABIO-RK:
12794
|
|
|
|
2-hydroxybenzoyl-CoA + O2 + NADH + H+ <=> 2,5-dihydroxybenzoyl-CoA + NAD+ + H2O
|
1.14.13.209
salicyloyl-CoA 5-hydroxylase
|
–
|
| |
BRENDA:
BR51496
KEGG:
R11056
MetaCyc:
RXN-11740
|
|
|
|
(2-hydroxybenzoyl)adenylate + CoA <=> 2-hydroxybenzoyl-CoA + AMP + H+
|
6.2.1.65
salicylate---CoA ligase
|
–
|
| |
BRENDA:
BR53123
KEGG:
R12641
MetaCyc:
RXN-11739
|
|
